Periorbital Pilomatrixoma

Pilomatrixoma is a rare benign tumor originating from the hair follicle matrix, most commonly developing during childhood and adolescence. While it can arise in various parts of the body, it is predominantly observed in the head and neck region during childhood. The incidence has been found as 1/824 based on the analysis of dermatohistopathological materials in the literature. This study aims to evaluate a case series of patients diagnosed histopathologically with pilomatrixoma. All cases presented with a painless, well-circumscribed, nontender, mobile mass located under the eyebrow. Simple excision was performed in all cases without any postoperative complications. Although slowly growth is typically anticipated, rapid growth was noted in 2 of our cases. In conclusion, although pilomatrixoma is rare, it should be considered in the differential diagnosis of masses in the periocular region, particularly those arising under the eyelid and eyebrow in childhood. Surgical excision remains the gold standard treatment for this condition.