Characteristics of Gut Microbiota in Inflammatory Bowel Disease and Colorectal Cancer

The constitution, and the proportion of gut microbiota, impact the occurrence of a series of diseases, for instance, inflammatory bowel disease and colorectal cancer. This article summarizes the characteristic gut microbiota of these two diseases, lists genes related to them, and proposes methods and their mechanisms to alleviate diseases. Among them, a significant ratio of individuals with Streptococcus bovine or Enterococcus bacteremia , ranging from 25% to 80%, and those with Streptococcus bovine or Enterococcus endocarditis , between 18% and 62%, are found to have a predisposition for potential colorectal tumors. Plus, individuals with high levels of Ruminococcus gnavus Clostridium bolteae , and Clostridium hathewayi , tend to be caught in inflammatory bowel disease. Original or engineered probiotics could be used either individually or combined with other therapies to alleviate diseases, and a series of optimization strategies can be taken into consideration.