Generalized gingivitis-related salivary proteomic profile in pregnant women with obesity: insights into biological mechanisms assessed by Tandem Mass Spectrometry
Pregnant women with obesity and generalized gingivitis exhibited a distinct salivary proteomic profile characterized by the up-regulation of immune-related proteins and downregulation of tissue-protective proteins. These findings suggest potential salivary biomarkers for detection and targeted management of periodontal inflammation in this high-risk population.
Authors
- Marília Afonso Rabelo Buzalaf (ORCID: https://orcid.org/0000-0002-5985-3951)
- Gérson Aparecido Foratori-Júnior (ORCID: https://orcid.org/0000-0003-4760-8948)
- Larissa Tercília Grizzo (ORCID: https://orcid.org/0000-0002-1469-5224)
- Talita Mendes Oliveira Ventura (ORCID: https://orcid.org/0000-0003-2101-1350)
- Laura Teodoro de Marchi (ORCID: https://orcid.org/0009-0007-4033-3351)
- Amanda Borges Pirondi (ORCID: https://orcid.org/0009-0005-2598-2228)
Institutions
- Universidade de São Paulo (BR)
- Universidade Brasil (BR)
Publication Details
- Journal
- Journal of Applied Oral Science
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1590/1678-7757-2025-0031
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação de Amparo à Pesquisa do Estado de São Paulo
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior