Screening of the Prodiginine Molecules as BH3-mimetics against theDeveloped Bcl-2 Antiapoptotic Chemotherapeutic Resistance: A MolecularDocking and ADMET Study Supported by Molecular DynamicsSimulations
Based on these results, butylcycloheptyl prodigiosin and prodigiosin-R2 could be more effective BH3 mimetics and should be further studied.
Authors
- Mohammed Menggad
- Zineb Azoubi
- Salaheddine Redouane (ORCID: https://orcid.org/0000-0002-5945-0386)
- E Ayoub (ORCID: https://orcid.org/0009-0009-0505-9793)
- Mouslim Assia
- Nadia ZOUGAGH
Institutions
- University of Hassan II Casablanca (MA)
Publication Details
- Journal
- Current Computer - Aided Drug Design
- Published
- 2025-05-09
- DOI
- https://doi.org/10.2174/0115734099367809250407094437
- Citations
- 2
- Primary Topic
- Microbial Metabolism and Applications
- Type
- article
- Field-Weighted Citation Impact
- 2.47