Genome-Wide Identification and Functional Prediction of LRR-RLK Family Genes in Foxtail Millet (Setaria italica) in Response to Stress

Leucine-rich repeat receptor-like kinases (LRR-RLKs) are involved in the regulation of various biological processes, including plant growth, development, and responses to biotic and abiotic stresses. Foxtail millet (<i>Setaria italica</i>), an important cereal crop, has been extensively studied for its stress tolerance mechanisms. In this study, we performed a comprehensive phylogenetic analysis and chromosomal mapping of LRR-RLK genes in <i>Setaria italica</i>. A total of 285 <i>SiLRR-RLK</i> genes were identified and classified into 12 subfamilies based on phylogenetic relationships. Chromosome localization analysis revealed that <i>SiLRR-RLK</i> genes are unevenly distributed across the chromosomes, with certain regions showing gene clusters. Functional analysis of these genes under biotic and abiotic stress conditions suggested that several <i>SiLRR-RLK</i> family members are involved in key stress response pathways. Expression profiling indicated differential expression patterns of <i>SiLRR-RLK</i> genes in response to various stresses, including drought, salinity, and pathogen infection, highlighting their potential roles in stress adaptation. In conclusion, the phylogenetic and functional analysis of the <i>SiLRR-RLK</i> gene family in <i>Setaria italica</i> provides valuable insights into their roles in stress responses and lays the groundwork for future studies aimed at enhancing stress tolerance in foxtail millet.