SSS: Signature-Sequence-Statistical Model for Exploring the Impact of Prenatal Depression on Newborns' Brain Using FNIRS

Research has shown that prenatal depression impacts newborn brain development, with previous studies primarily using statistical analysis. This paper introduces deep learning models to investigate this effect, using rsfNIRS data to predict maternal prenatal depression. Traditional fNIRS classification methods struggle with high-dimensional dependencies and global features, leading to unsatisfactory performance. To overcome this, we propose the SSS model, which leverages path Signature, temporal Sequence, and global Statistical features, achieving an accuracy of 73% and an F1-score of 84%. Our experiments reveal that using data from the entire brain yields the best classification results, suggesting that prenatal depression may affect the newborn's entire brain.

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Publication Details

Published
2025-04-14
DOI
https://doi.org/10.1109/isbi60581.2025.10980991
Primary Topic
Neonatal and fetal brain pathology
Type
article
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article

SSS: Signature-Sequence-Statistical Model for Exploring the Impact of Prenatal Depression on Newborns' Brain Using FNIRS

Lei Hua, Xiaofen Xing, Zhaojin Chen, Jiyu Qian et al.
Neonatal and fetal brain pathology
article

SSS: Signature-Sequence-Statistical Model for Exploring the Impact of Prenatal Depression on Newborns' Brain Using FNIRS

Lei Hua, Xiaofen Xing, Zhaojin Chen, Jiyu Qian, Xin Zhang, Xuejiao Li, Chengfang Xu, Guodong Liang, Yingxue Yao, Yu Shen, Zicong Zheng
article en

Abstract

Research has shown that prenatal depression impacts newborn brain development, with previous studies primarily using statistical analysis. This paper introduces deep learning models to investigate this effect, using rsfNIRS data to predict maternal prenatal depression. Traditional fNIRS classification methods struggle with high-dimensional dependencies and global features, leading to unsatisfactory performance. To overcome this, we propose the SSS model, which leverages path Signature, temporal Sequence, and global Statistical features, achieving an accuracy of 73% and an F1-score of 84%. Our experiments reveal that using data from the entire brain yields the best classification results, suggesting that prenatal depression may affect the newborn's entire brain.

Sun Yat-sen University (CN), Third Affiliated Hospital of Sun Yat-sen University (CN), South China University of Technology (CN)
Openalex Percentile: Top 86%
Neonatal and fetal brain pathology
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