Contrast-Free Myocardial Scar Segmentation in Cine MRI using Motion and Texture Fusion

Late gadolinium enhancement MRI (LGE MRI) is the gold standard for the detection of myocardial scars post myocardial infarction (MI). LGE MRI requires the injection of a contrast agent, which carries potential side effects and increases scanning time and patient discomfort. To address these issues, we propose a novel framework that combines cardiac motion observed in cine MRI with image texture information to segment the myocardium and scar tissue in the left ventricle. Cardiac motion tracking can be formulated as a full cardiac image cycle registration problem, which can be solved via deep neural networks. Experimental results prove that the proposed method can achieve scar segmentation based on non-contrast cine images with comparable accuracy to LGE MRI. This demonstrates its potential as an alternative to contrast-enhanced techniques for scar detection.

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Publication Details

Published
2025-04-14
DOI
https://doi.org/10.1109/isbi60581.2025.10981129
Citations
2
Primary Topic
Image Processing Techniques and Applications
Type
article
Field-Weighted Citation Impact
2.27
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article

Contrast-Free Myocardial Scar Segmentation in Cine MRI using Motion and Texture Fusion

Xiahai Zhuang, Vicente Grau, Betty Raman, Guang Yang et al.
2 citations
Image Processing Techniques and Applications
2.27
article

Contrast-Free Myocardial Scar Segmentation in Cine MRI using Motion and Texture Fusion

Xiahai Zhuang, Vicente Grau, Betty Raman, Guang Yang, Xicheng Sheng, Jingkun Chen, Lei Li, Shan Yang
article en
2 citations

Abstract

Late gadolinium enhancement MRI (LGE MRI) is the gold standard for the detection of myocardial scars post myocardial infarction (MI). LGE MRI requires the injection of a contrast agent, which carries potential side effects and increases scanning time and patient discomfort. To address these issues, we propose a novel framework that combines cardiac motion observed in cine MRI with image texture information to segment the myocardium and scar tissue in the left ventricle. Cardiac motion tracking can be formulated as a full cardiac image cycle registration problem, which can be solved via deep neural networks. Experimental results prove that the proposed method can achieve scar segmentation based on non-contrast cine images with comparable accuracy to LGE MRI. This demonstrates its potential as an alternative to contrast-enhanced techniques for scar detection.

Fudan University (CN), University of Oxford (GB), Zhongshan Hospital (CN), Science Oxford (GB)
Zero hunger
Openalex Percentile: Top 11%
Image Processing Techniques and Applications
2.27
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Contrast-Free Myocardial Scar Segmentation in Cine MRI using Motion and Texture Fusion — Xiahai Zhuang, Vicente Grau, et al. · (2025) | TGRS Research Map | TGRS