Melanoma Detection with Uncertainty Quantification

Early detection of melanoma is crucial for improving survival rates. Current detection tools often utilize data-driven machine learning methods but often overlook the full integration of multiple datasets. We combine publicly available datasets to enhance data diversity, allowing numerous experiments to train and evaluate various classifiers. We then calibrate them to minimize misdiagnoses by incorporating uncertainty quantification. Our experiments on benchmark datasets show accuracies of up to 93.2% before and 97.8% after applying uncertainty-based rejection, leading to a reduction in misdiagnoses by over 40.5%. Our code and data are publicly available<sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup><sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup>Our GitHub repository, https: / /mpsych. org /melanoma, and a web-based interface<sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup><sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup>0ur Web interface, https: / /mpsych. gi thub. io/melanoma/ for quick melanoma detection of user-supplied images is also provided.

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Published
2025-04-14
DOI
https://doi.org/10.1109/isbi60581.2025.10981143
Primary Topic
Computational Drug Discovery Methods
Type
article
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article

Melanoma Detection with Uncertainty Quantification

SangHyuk Kim, Daniel Haehn, Brian Matejek, Edward Gaibor
Computational Drug Discovery Methods
article

Melanoma Detection with Uncertainty Quantification

SangHyuk Kim, Daniel Haehn, Brian Matejek, Edward Gaibor
article en

Abstract

Early detection of melanoma is crucial for improving survival rates. Current detection tools often utilize data-driven machine learning methods but often overlook the full integration of multiple datasets. We combine publicly available datasets to enhance data diversity, allowing numerous experiments to train and evaluate various classifiers. We then calibrate them to minimize misdiagnoses by incorporating uncertainty quantification. Our experiments on benchmark datasets show accuracies of up to 93.2% before and 97.8% after applying uncertainty-based rejection, leading to a reduction in misdiagnoses by over 40.5%. Our code and data are publicly available<sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup><sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup>Our GitHub repository, https: / /mpsych. org /melanoma, and a web-based interface<sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup><sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup>0ur Web interface, https: / /mpsych. gi thub. io/melanoma/ for quick melanoma detection of user-supplied images is also provided.

SRI International (US), University of Massachusetts Boston (US)
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Computational Drug Discovery Methods
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