EDA: Enhanced Domain-Adversarial Training for Anatomical Landmark Detection

Manually annotating anatomical landmarks in medical images requires experienced clinicians and is a labor-intensive process. However, recent AI-assisted methods for landmark detection often rely on the training and test data originating from the same domain. This work introduces a novel unsupervised domain adaptation (UDA) framework aimed at anatomical landmark detection from a medical image, designed to bridge the gap between a source domain with labels and an unlabeled target domain. Specifically, we have developed a new Domain-Adversarial Network that incorporates skip connections to transfer and fuse high-resolution feature maps. Additionally, we proposed Dynamic Gaussian Learning, which allows the model to escape from local error regions. We carry out experiments on landmark detection for both head and chest, and the results demonstrate that our method achieves state-of-the-art performances in each experiment.