Leveraging Insights from KNN and LSTM Models for Alzheimer’s Disease Early Detection

In this research, soft computing methods are explored for the early detection of dementia from EEG signal analysis. The study extract features from key frequency bands (Delta, Theta, Alpha, Beta) and uses the machine learning models such as K Nearest Neighbors (KNN) and Long Short Term Memory (LSTM) networks to identify small cognitive changes. Specifically, the LSTM model exhibits exceptional performance, particularly with increased sensitivity and specificity, especially in the Alpha and Beta bands, for early stage dementia detection. This work provides a promising alternate to costly existing methods and contributes to the development of noninvasive, scalable diagnostic tools for dementia. Early detection by observing the synchrony across the brain lobe could help improve diagnosis and contribute to future AI based healthcare applications.

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Publication Details

Published
2025-02-06
DOI
https://doi.org/10.1109/aide64228.2025.10986896
Primary Topic
Machine Learning in Healthcare
Type
article
Field-Weighted Citation Impact
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article

Leveraging Insights from KNN and LSTM Models for Alzheimer’s Disease Early Detection

Virendra Shete, Rageshri Bakare, Magda Tsolaki, Ioannis Yiannis Kompatsiaris
Machine Learning in Healthcare
article

Leveraging Insights from KNN and LSTM Models for Alzheimer’s Disease Early Detection

Virendra Shete, Rageshri Bakare, Magda Tsolaki, Ioannis Yiannis Kompatsiaris
article en

Abstract

In this research, soft computing methods are explored for the early detection of dementia from EEG signal analysis. The study extract features from key frequency bands (Delta, Theta, Alpha, Beta) and uses the machine learning models such as K Nearest Neighbors (KNN) and Long Short Term Memory (LSTM) networks to identify small cognitive changes. Specifically, the LSTM model exhibits exceptional performance, particularly with increased sensitivity and specificity, especially in the Alpha and Beta bands, for early stage dementia detection. This work provides a promising alternate to costly existing methods and contributes to the development of noninvasive, scalable diagnostic tools for dementia. Early detection by observing the synchrony across the brain lobe could help improve diagnosis and contribute to future AI based healthcare applications.

Information Technologies Institute (GR), Centre for Research and Technology Hellas (GR), Greek Association of Alzheimer's Disease and Related Disorders (GR), MIT Art, Design and Technology University (IN)
Openalex Percentile: Top 95%
Machine Learning in Healthcare
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