DiffKAN-Inpainting: KAN-Based Diffusion Model for Brain Tumor Inpainting

Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and treatment. Most conventional U-Net-based generative models, however, often face challenges in capturing the complex, nonlinear latent representations inherent in brain imaging. In order to accomplish high-quality healthy brain tissue reconstruction, this work proposes DiffKAN-Inpainting, an innovative method that blends diffusion models with the Kolmogorov-Arnold Networks architecture. During the denoising process, we introduce the RePaint method and tumor information to generate images with a higher fidelity and smoother margin. Both qualitative and quantitative results demonstrate that as compared to the state-of-the-art methods, our proposed DiffKAN-Inpainting inpaints more detailed and realistic reconstructions on the BraTS dataset. The knowledge gained from ablation study provide insights for future research to balance performance with computing cost.

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Publication Details

Published
2025-04-14
DOI
https://doi.org/10.1109/isbi60581.2025.10980990
Citations
2
Primary Topic
Generative Adversarial Networks and Image Synthesis
Type
article
Field-Weighted Citation Impact
2.55
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article

DiffKAN-Inpainting: KAN-Based Diffusion Model for Brain Tumor Inpainting

Theodoros N. Arvanitis, Tianli Tao, Ziyang Wang, Han Zhang et al.
2 citations
Generative Adversarial Networks and Image Synthesis
2.55
article

DiffKAN-Inpainting: KAN-Based Diffusion Model for Brain Tumor Inpainting

Theodoros N. Arvanitis, Tianli Tao, Ziyang Wang, Han Zhang, Le Zhang
article en
2 citations

Abstract

Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and treatment. Most conventional U-Net-based generative models, however, often face challenges in capturing the complex, nonlinear latent representations inherent in brain imaging. In order to accomplish high-quality healthy brain tissue reconstruction, this work proposes DiffKAN-Inpainting, an innovative method that blends diffusion models with the Kolmogorov-Arnold Networks architecture. During the denoising process, we introduce the RePaint method and tumor information to generate images with a higher fidelity and smoother margin. Both qualitative and quantitative results demonstrate that as compared to the state-of-the-art methods, our proposed DiffKAN-Inpainting inpaints more detailed and realistic reconstructions on the BraTS dataset. The knowledge gained from ablation study provide insights for future research to balance performance with computing cost.

ShanghaiTech University (CN), The Alan Turing Institute (GB), University of Birmingham (GB)
Openalex Percentile: Top 11%
Generative Adversarial Networks and Image Synthesis
2.55
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