DiffKAN-Inpainting: KAN-Based Diffusion Model for Brain Tumor Inpainting
Brain tumors delay the standard preprocessing workflow for further examination. Brain inpainting offers a viable, although difficult, solution for tumor tissue processing, which is necessary to improve the precision of the diagnosis and treatment. Most conventional U-Net-based generative models, however, often face challenges in capturing the complex, nonlinear latent representations inherent in brain imaging. In order to accomplish high-quality healthy brain tissue reconstruction, this work proposes DiffKAN-Inpainting, an innovative method that blends diffusion models with the Kolmogorov-Arnold Networks architecture. During the denoising process, we introduce the RePaint method and tumor information to generate images with a higher fidelity and smoother margin. Both qualitative and quantitative results demonstrate that as compared to the state-of-the-art methods, our proposed DiffKAN-Inpainting inpaints more detailed and realistic reconstructions on the BraTS dataset. The knowledge gained from ablation study provide insights for future research to balance performance with computing cost.
Authors
- Theodoros N. Arvanitis (ORCID: https://orcid.org/0000-0001-5473-135X)
- Tianli Tao
- Ziyang Wang (ORCID: https://orcid.org/0000-0002-3174-1894)
- Han Zhang (ORCID: https://orcid.org/0000-0002-0166-1973)
- Le Zhang (ORCID: https://orcid.org/0000-0002-3848-0017)
Institutions
- ShanghaiTech University (CN)
- The Alan Turing Institute (GB)
- University of Birmingham (GB)
Publication Details
- Published
- 2025-04-14
- DOI
- https://doi.org/10.1109/isbi60581.2025.10980990
- Citations
- 2
- Primary Topic
- Generative Adversarial Networks and Image Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 2.55