Treatment decisions for intermediate-sized brain metastases in or near the motor cortex among the neuro-oncology community
Surgical resection is preferred in patients with larger tumors, with neurologic symptoms that are unresponsive to dexamethasone, and in patients receiving immunotherapy. Future investigations should compare the effectiveness of surgical resection and stereotactic radiosurgery, and the effects on survival and quality of life in patients with BM in or near the motor cortex in a prospective and preferable randomized manner.
Authors
- Rob J.A. Nabuurs
- Dieta Brandsma (ORCID: https://orcid.org/0000-0001-7998-9904)
- Charissa Jessurun (ORCID: https://orcid.org/0000-0002-9569-1515)
- Annette Compter (ORCID: https://orcid.org/0000-0001-9732-2150)
- Paula Valerie ter Wengel (ORCID: https://orcid.org/0000-0003-1073-8239)
- Marike L. D. Broekman (ORCID: https://orcid.org/0000-0002-0226-0119)
- Philip C. De Witt Hamer (ORCID: https://orcid.org/0000-0003-2988-8544)
- Alfred Kloet (ORCID: https://orcid.org/0000-0002-3974-4774)
Institutions
- Leiden University Medical Center (NL)
- Massachusetts General Hospital (US)
- Medisch Centrum Haaglanden (NL)
- Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital (NL)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Brain and Spine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.bas.2025.104278
- Primary Topic
- Brain Metastases and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00