PNOC009: Convection-enhanced delivery of liposomal irinotecan in patients with newly diagnosed diffuse intrinsic pontine glioma
Repeated CED of nal-IRI in patients with DIPG demonstrated an acceptable risk profile with reasonable tumor coverage. Additional investigations utilizing this strategy should be evaluated in a larger patient cohort to determine efficacy.
Authors
- Raoull Hoogendijk (ORCID: https://orcid.org/0000-0002-8033-2093)
- Alyssa Terry Reddy (ORCID: https://orcid.org/0000-0002-5052-0501)
- Anuradha Banerjee (ORCID: https://orcid.org/0000-0002-1694-4319)
- Michael D. Prados (ORCID: https://orcid.org/0000-0002-9630-2075)
- Schuyler Stoller (ORCID: https://orcid.org/0000-0002-1931-7521)
- Shannon Raber (ORCID: https://orcid.org/0000-0002-0297-0559)
- Alex Y Lu (ORCID: https://orcid.org/0000-0003-1606-6306)
- Cassie Kline (ORCID: https://orcid.org/0000-0001-7765-7690)
- Eva Wembacher-Schroeder
- Annette Molinaro
- Carly Hoffman (ORCID: https://orcid.org/0000-0003-0831-4285)
- Sabine Mueller (ORCID: https://orcid.org/0000-0002-3452-5150)
- Nalin Gupta (ORCID: https://orcid.org/0000-0001-9539-7052)
Institutions
- Children's Hospital of Philadelphia (US)
- University of California, San Francisco (US)
- University of Zurich (CH)
- University Medical Center (US)
- Blood Systems Research Institute (US)
- University Hospital of Zurich (CH)
- Center for Cancer and Blood Disorders (US)
- Princess Máxima Center (NL)
- Erasmus MC Cancer Institute (NL)
- Neurological Surgery (US)
- Brainlab (Germany) (DE)
- University of Pennsylvania (US)
Publication Details
- Journal
- Neuro-Oncology Advances
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/noajnl/vdaf093
- Citations
- 1
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.63
Funders
- Pediatric Brain Tumor Foundation