Childhood Asthma and Allergy Are Related to Accelerated Epigenetic Aging

We found an increase in epigenetic age in children with allergic diseases from LISA. Our results suggest that epigenetic age acceleration seems to be related to the persistent burden of allergic diseases, but not to non-symptomatic aeroallergen sensitization.

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Publication Details

Journal
Allergy
Published
2025-05-10
DOI
https://doi.org/10.1111/all.16583
Citations
2
Primary Topic
Epigenetics and DNA Methylation
Type
article
Field-Weighted Citation Impact
1.61

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article

Childhood Asthma and Allergy Are Related to Accelerated Epigenetic Aging

Zhebin Yu, Anke Hüls, Elisabeth Thiering, Erik Melén et al.
2 citations
Allergy
Epigenetics and DNA Methylation
1.61
article

Childhood Asthma and Allergy Are Related to Accelerated Epigenetic Aging

Zhebin Yu, Anke Hüls, Elisabeth Thiering, Erik Melén, Yueli Yao, Simon Kebede Merid, Miriam Leskien, Olena Gruzieva, Marie Standl, Mélanie Waldenberger, Stephan Weidinger, Annette Peters
article en
2 citations

Abstract

We found an increase in epigenetic age in children with allergic diseases from LISA. Our results suggest that epigenetic age acceleration seems to be related to the persistent burden of allergic diseases, but not to non-symptomatic aeroallergen sensitization.

AllergyVol. 80(7)
Emory University (US), Karolinska Institutet (SE), Helmholtz Zentrum München (DE), German Center for Pediatric and Adolescent Rheumatology (DE), Stockholm South General Hospital (SE), University Hospital Schleswig-Holstein (DE), Sachs' Children and Youth Hospital (SE), German Center for Lung Research (DE), Centre for Palaeogenetics (SE), Ludwig-Maximilians-Universität München (DE), University of Lübeck (DE)
European Commission, Bundesministerium für Bildung und Forschung, Hjärt-Lungfonden, Karolinska Institutet, Vetenskapsrådet, Helmholtz-Zentrum für Umweltforschung, Forskningsrådet om Hälsa, Arbetsliv och Välfärd, Bundesministerium für Bildung, Wissenschaft, Forschung und Technologie, European Research Council, Leibniz-Gemeinschaft, Helmholtz Zentrum München, Uppsala Multidisciplinary Center for Advanced Computational Science
Good health and well-being
Openalex Percentile: Top 17%
Epigenetics and DNA Methylation
1.61
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