Childhood Asthma and Allergy Are Related to Accelerated Epigenetic Aging
We found an increase in epigenetic age in children with allergic diseases from LISA. Our results suggest that epigenetic age acceleration seems to be related to the persistent burden of allergic diseases, but not to non-symptomatic aeroallergen sensitization.
Authors
- Zhebin Yu (ORCID: https://orcid.org/0000-0001-9392-5624)
- Anke Hüls (ORCID: https://orcid.org/0000-0002-6005-417X)
- Elisabeth Thiering (ORCID: https://orcid.org/0000-0002-5429-9584)
- Erik Melén (ORCID: https://orcid.org/0000-0002-8248-0663)
- Yueli Yao (ORCID: https://orcid.org/0000-0003-3230-1513)
- Simon Kebede Merid (ORCID: https://orcid.org/0000-0001-5974-7676)
- Miriam Leskien (ORCID: https://orcid.org/0009-0004-6884-6640)
- Olena Gruzieva (ORCID: https://orcid.org/0000-0003-4147-5654)
- Marie Standl (ORCID: https://orcid.org/0000-0002-5345-2049)
- Mélanie Waldenberger (ORCID: https://orcid.org/0000-0003-0583-5093)
- Stephan Weidinger (ORCID: https://orcid.org/0000-0003-3944-252X)
- Annette Peters (ORCID: https://orcid.org/0000-0001-6645-0985)
Institutions
- Emory University (US)
- Karolinska Institutet (SE)
- Helmholtz Zentrum München (DE)
- German Center for Pediatric and Adolescent Rheumatology (DE)
- Stockholm South General Hospital (SE)
- University Hospital Schleswig-Holstein (DE)
- Sachs' Children and Youth Hospital (SE)
- German Center for Lung Research (DE)
- Centre for Palaeogenetics (SE)
- Ludwig-Maximilians-Universität München (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- Allergy
- Published
- 2025-05-10
- DOI
- https://doi.org/10.1111/all.16583
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- European Commission
- Bundesministerium für Bildung und Forschung
- Hjärt-Lungfonden
- Karolinska Institutet
- Vetenskapsrådet
- Helmholtz-Zentrum für Umweltforschung
- Forskningsrådet om Hälsa, Arbetsliv och Välfärd
- Bundesministerium für Bildung, Wissenschaft, Forschung und Technologie
- European Research Council
- Leibniz-Gemeinschaft
- Helmholtz Zentrum München
- Uppsala Multidisciplinary Center for Advanced Computational Science