Giant Mesenteric Lipoma in a 10-Year-Old Girl: A Case Report

Mesenteric lipomas are rare benign tumors, with pediatric cases constituting fewer than 50 reported instances. We present a 10-year-old girl with a 19 cm mesenteric lipoma manifesting as progressive abdominal distension. Imaging revealed a well-circumscribed, homogeneous fat-density mass on CT, consistent with a benign lipoma. Surgical resection with en bloc jejunal excision was performed due to vascular adhesions. Histopathology confirmed a lipoma with free margins (R0). The discussion highlights the role of MRI in differentiating lipomas from sarcomas and reviews the excellent prognosis post-resection. This case underscores the importance of imaging-guided management to avoid unnecessary biopsies in pediatric mesenteric masses.