Modeling the Impact and Cost of a Culture-Dependent Molecular Test for Antimicrobial Resistance in Resource-Limited Settings
In high AMR burden settings with blood culture infrastructure supporting fast turnaround times, a molecular test could improve health outcomes of bloodstream infection. Impact is limited by delayed turnaround times and the effectiveness of empiric therapy. Molecular diagnostics implemented at $100 or less can generate healthcare-system cost savings, supporting their adoption to improve health outcomes and reduce AMR while remaining cost-neutral.
Authors
- Cecilia Ferreyra (ORCID: https://orcid.org/0000-0001-5480-7940)
- Shaukat Khan (ORCID: https://orcid.org/0000-0001-7247-4190)
- Kyra H. Grantz (ORCID: https://orcid.org/0000-0002-2319-5010)
- Megan A Hansen (ORCID: https://orcid.org/0009-0007-0003-7179)
- Joshua M Chevalier (ORCID: https://orcid.org/0000-0001-8873-6669)
- Veronicah Chuchu (ORCID: https://orcid.org/0000-0002-4584-9708)
- Benjamin Blümel (ORCID: https://orcid.org/0000-0002-3227-4941)
- Brooke E Nichols (ORCID: https://orcid.org/0000-0003-4682-4999)
- Birgitta Gleeson (ORCID: https://orcid.org/0009-0003-0791-7735)
Institutions
- Boston University (US)
- FIND (CH)
- University of the Witwatersrand (ZA)
- Amsterdam Institute for Global Health and Development (NL)
- Amsterdam University Medical Centers (NL)
- Impact (CA)
- University of Amsterdam (NL)
Publication Details
- Journal
- Clinical Infectious Diseases
- Published
- 2025-05-09
- DOI
- https://doi.org/10.1093/cid/ciaf236
- Citations
- 1
- Primary Topic
- Bacterial Identification and Susceptibility Testing
- Type
- article
- Field-Weighted Citation Impact
- 1.32