Genotypic Distribution of Alpha-Like Proteins in Group B <i>Streptococcus</i> Strains Isolated in Korea: Implications for Vaccine Coverage
Although the distribution of <i>alp</i> genotypes differed between invasive and non-invasive strains, the proportion of bca and rib was substantial. Therefore, Alp protein vaccine containing Rib and Cα antigens is expected to provide protection against prevalent GBS strains in Korea. Additional epidemiological studies on GBS vaginal colonization in pregnant women and invasive neonatal strains are needed to support early neonatal sepsis prevention in these high-risk groups.
Authors
- Ji Hyen Lee (ORCID: https://orcid.org/0000-0002-2234-1055)
- Kyung‐Hyo Kim (ORCID: https://orcid.org/0000-0002-0333-6808)
- Hye‐Kyung Cho (ORCID: https://orcid.org/0000-0003-0990-1350)
- Dae Sun Jo (ORCID: https://orcid.org/0000-0002-3141-9539)
- Han Wool Kim (ORCID: https://orcid.org/0000-0003-3463-3060)
- Hyunju Lee (ORCID: https://orcid.org/0000-0003-0107-0724)
Institutions
- Ewha Womans University (KR)
- Seoul National University Bundang Hospital (KR)
- Hallym University Sacred Heart Hospital (KR)
- Jeonbuk National University (KR)
Publication Details
- Journal
- Infection and Chemotherapy
- Published
- 2025-01-01
- DOI
- https://doi.org/10.3947/ic.2024.0127
- Primary Topic
- Neonatal and Maternal Infections
- Type
- article
- Field-Weighted Citation Impact
- 0.00