Case Report: A rare case of mixed epithelial and stromal tumor of the kidney in an adolescent: imaging findings and literature review

Mixed epithelial and stromal tumor of the kidney (MESTK) is an unusual biphasic benign renal neoplasm. It predominantly occurs in perimenopausal women, with only eight cases reported in children. Owing to its rarity, only limited radiological information has been reported in the literature, in none of the previous pediatric cases were both CT and MRI findings of the tumor provided. Herein, we report a rare case of MESTK in a 13-year-old girl. This case was the largest observed in children to date. Findings from our report provide novel insights into the MRI features of a large pediatric MESTK and indicate the importance of MRI for observing adipose components and the absence of diffusion restriction within the tumor. Radiologists should consider the possibility of MESTK in children when they observe a large, solid renal tumor without diffusion restriction in children.

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Journal
Frontiers in Pediatrics
Published
2025-05-08
DOI
https://doi.org/10.3389/fped.2025.1550425
Primary Topic
Renal and related cancers
Type
article
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article

Case Report: A rare case of mixed epithelial and stromal tumor of the kidney in an adolescent: imaging findings and literature review

Guang Fu, Xudan Yang, Rong Xiao, Tao Lu
Frontiers in Pediatrics
Renal and related cancers
article

Case Report: A rare case of mixed epithelial and stromal tumor of the kidney in an adolescent: imaging findings and literature review

Guang Fu, Xudan Yang, Rong Xiao, Tao Lu
article en

Abstract

Mixed epithelial and stromal tumor of the kidney (MESTK) is an unusual biphasic benign renal neoplasm. It predominantly occurs in perimenopausal women, with only eight cases reported in children. Owing to its rarity, only limited radiological information has been reported in the literature, in none of the previous pediatric cases were both CT and MRI findings of the tumor provided. Herein, we report a rare case of MESTK in a 13-year-old girl. This case was the largest observed in children to date. Findings from our report provide novel insights into the MRI features of a large pediatric MESTK and indicate the importance of MRI for observing adipose components and the absence of diffusion restriction within the tumor. Radiologists should consider the possibility of MESTK in children when they observe a large, solid renal tumor without diffusion restriction in children.

Frontiers in PediatricsVol. 13
University of Electronic Science and Technology of China (CN)
Good health and well-being
Openalex Percentile: Top 91%
Renal and related cancers
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Case Report: A rare case of mixed epithelial and stromal tumor of the kidney in an adolescent: imaging findings and literature review — Guang Fu, Xudan Yang, et al. · Frontiers in Pediatrics (2025) | TGRS Research Map | TGRS