PITX1 as a grading, prognostic and tumor-infiltrating immune cells marker for chondrosarcoma: a public database-based immunoassay and tissue sample analysis

PITX1 is a novel biomarker for distinguishing between high-grade and low-grade CHS, serving as a prognostic indicator for patients with this condition and presenting a promising target for immunotherapy. These findings offer innovative insights into the treatment of CHS.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-04-11
DOI
https://doi.org/10.3389/fonc.2025.1477649
Primary Topic
Cancer-related molecular mechanisms research
Type
article
Field-Weighted Citation Impact
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article

PITX1 as a grading, prognostic and tumor-infiltrating immune cells marker for chondrosarcoma: a public database-based immunoassay and tissue sample analysis

Shubiao Chen, Dongchen Liu, Weiqing Lu, Lan Hu et al.
Frontiers in Oncology
Cancer-related molecular mechanisms research
article

PITX1 as a grading, prognostic and tumor-infiltrating immune cells marker for chondrosarcoma: a public database-based immunoassay and tissue sample analysis

Shubiao Chen, Dongchen Liu, Weiqing Lu, Lan Hu, Jinghao Zhang, Zhang Ying, Lei Xie, Zikun Huang
article en

Abstract

PITX1 is a novel biomarker for distinguishing between high-grade and low-grade CHS, serving as a prognostic indicator for patients with this condition and presenting a promising target for immunotherapy. These findings offer innovative insights into the treatment of CHS.

Frontiers in OncologyVol. 15
Shantou University (CN), Cancer Hospital of Shantou University Medical College (CN), First Affiliated Hospital of Shantou University Medical College (CN), Shantou University Medical College (CN)
Good health and well-being
Openalex Percentile: Top 87%
Cancer-related molecular mechanisms research
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