Proteomic associations with fluctuation and long‐term changes in <scp>BMI</scp> : A 40‐year follow‐up study
This study highlights significant associations between plasma proteins and long-term BMI changes and fluctuations, with no evidence of PRS<sub>BMI</sub>-protein interactions influencing BMI trends. These findings underscore the substantial role of environmental factors in shaping proteome-BMI associations over adulthood.
Authors
- Jaakko A. Kaprio (ORCID: https://orcid.org/0000-0002-3716-2455)
- Gabin Drouard (ORCID: https://orcid.org/0000-0002-3227-8483)
- Miina Ollikainen (ORCID: https://orcid.org/0000-0003-3661-7400)
- Teemu Palviainen (ORCID: https://orcid.org/0000-0002-7847-8384)
- Karri Silventoinen (ORCID: https://orcid.org/0000-0003-1759-3079)
- Xiaoling Wang (ORCID: https://orcid.org/0000-0001-9290-7926)
- Alvaro Obeso
Institutions
- University of Helsinki (FI)
- University of the Basque Country (ES)
- Augusta University (US)
- Minerva Foundation (FI)
- Institute for Molecular Medicine Finland (FI)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1111/dom.16448
- Citations
- 3
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 5.45
Funders
- Helsingin Yliopisto
- HORIZON EUROPE Framework Programme
- Biotieteiden ja Ympäristön Tutkimuksen Toimikunta
- National Heart, Lung, and Blood Institute
- HORIZON EUROPE European Innovation Council