Genetic Variability in Cisplatin Metabolism in Kidney Injury in Patients With Head and Neck Squamous Cell Carcinoma Undergoing Definitive Chemoradiotherapy

Our data suggest that isolated and combined SNVs in genes enrolled in CDDP metabolism can be used to select patients for treatments that spare the kidneys from adverse effects.

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Publication Details

Journal
Head & Neck
Published
2025-05-08
DOI
https://doi.org/10.1002/hed.28179
Citations
1
Primary Topic
Chemotherapy-induced organ toxicity mitigation
Type
article
Field-Weighted Citation Impact
1.47

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article

Genetic Variability in Cisplatin Metabolism in Kidney Injury in Patients With Head and Neck Squamous Cell Carcinoma Undergoing Definitive Chemoradiotherapy

Carmen Sílvia Passos Lima, Ericka Francislaine Dias Costa, Ana Maria Castro Ferreira, Marilda Mazzali et al.
1 citations
Head & Neck
Chemotherapy-induced organ toxicity mitigation
1.47
article

Genetic Variability in Cisplatin Metabolism in Kidney Injury in Patients With Head and Neck Squamous Cell Carcinoma Undergoing Definitive Chemoradiotherapy

Carmen Sílvia Passos Lima, Ericka Francislaine Dias Costa, Ana Maria Castro Ferreira, Marilda Mazzali, Gustavo Jacob Lourenço
article en
1 citations

Abstract

Our data suggest that isolated and combined SNVs in genes enrolled in CDDP metabolism can be used to select patients for treatments that spare the kidneys from adverse effects.

Head & NeckVol. 47(10)
Universidade Estadual de Campinas (UNICAMP) (BR)
Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Universidade Estadual de Campinas
Openalex Percentile: Top 20%
Chemotherapy-induced organ toxicity mitigation
1.47
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