Linfoma cutâneo epiteliotrópico em cão jovem

The article addresses the diagnosis and treatment of epitheliotropic cutaneous lymphoma in a 1 year and 6 months old dog, which is atypical given that cutaneous lymphoma generally affects older dogs. The disease is a hematopoietic neoplasm that originates from malignant lymphocytes and can manifest itself in the skin, although it is relatively rare. Cutaneous lymphoma can be classified as epitheliotropic or non-epitheliotropic, depending on the location of the neoplastic cells. In the case described, the dog, a Cavalier King Charles breed, presented symptoms such as prostration, nodulations and significant hematological changes, including anemia and thrombocytopenia. After investigations, including aspiration cytology and histopathological examinations, he was diagnosed with epitheliotropic cutaneous lymphoma. Chemotherapy treatment with lomustine was initiated, showing initial efficacy with 90% remission of skin lesions. However, there was a recurrence of nodules, which led to an adjustment of the lomustine dose and intensification of treatment. Unfortunately, despite treatment attempts, the dog presented a rapid relapse and deterioration in general condition, culminating in euthanasia,149 days after the first consultation, above reported cases, which range from 63 to 83 days of survival. This report highlights the importance of ongoing assessment and monitoring of chemotherapy side effects, as well as the need to consider the possibility of cutaneous lymphoma in younger dogs.