Dual energy CT-derived quantitative parameters and hematological characteristics predict pathological complete response in neoadjuvant chemoradiotherapy esophageal squamous cell carcinoma patients
Dual-layer DECT derived ECV fraction and AEF are valuable predictors for pCR in ESCC patients after nCRT. The model combined DECT quantitative parameters and clinical features might be used as a non-invasive tool for individualized treatment decision of those ESCC patients. This study validates the role of DECT in pCR assessment for ESCC and a large external cohort is warranted to ensure the robustness of the proposed DECT evaluation criteria.
Authors
- Mingming Nie (ORCID: https://orcid.org/0000-0003-3067-1588)
- Yuanyuan Yan (ORCID: https://orcid.org/0000-0003-0432-5518)
- Yong Huang (ORCID: https://orcid.org/0000-0003-2652-8586)
- Yong Yin (ORCID: https://orcid.org/0000-0002-0741-7023)
- Xihuang Lin (ORCID: https://orcid.org/0000-0001-7250-0539)
- Yongbin Cui
- Miaomiao Li (ORCID: https://orcid.org/0000-0001-7678-687X)
- Baosheng Li (ORCID: https://orcid.org/0000-0002-5390-7269)
- Zhao Jun-feng
- Shushan Dong (ORCID: https://orcid.org/0000-0001-5466-7028)
- Qianyu Liu
Institutions
- Shandong University (CN)
- Philips (China) (CN)
- Shandong Tumor Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-05-10
- DOI
- https://doi.org/10.1186/s12876-025-03964-2
- Citations
- 4
- Primary Topic
- Advanced X-ray and CT Imaging
- Type
- article
- Field-Weighted Citation Impact
- 2.70
Funders
- National Natural Science Foundation of China