Polyneuropathy due to n-Hexane Intoxication – A Case Series
n -Hexane, a volatile organic chemical, is notorious for its neurotoxicity in occupational settings. We present four patients working in a needle manufacturing factory who presented with polyneuropathy after exposure to n -hexane by inhalation. Cerebrospinal fluid showed albuminocytological dissociation. Nerve conduction study (NCV) showed primary demyelination with secondary axonal polyneuropathy. Excluding the other possible causes, the diagnosis of n -hexane neuropathy was kept. Patients were managed with symptomatic treatment and showed marked improvement in 6-month follow-up.
Authors
- Khichar Shubhakaran (ORCID: https://orcid.org/0000-0001-5515-7572)
- Pradeep Lalwani
- Nidhi Yadav (ORCID: https://orcid.org/0000-0003-0751-6010)
Publication Details
- Journal
- Annals of Indian Academy of Neurology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.4103/aian.aian_39_25
- Citations
- 1
- Primary Topic
- Carcinogens and Genotoxicity Assessment
- Type
- article
- Field-Weighted Citation Impact
- 0.94