From variability to stability: Sensitivity of network properties in IBD human gut microbiome studies

Caution is needed with network-based approaches, as even small variations, stemming from sources of microbiome variability, can affect results and reproducibility. The relatively stable dysbiosis in IBD could pose challenges for microbiome-directed therapies.

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Publication Details

Journal
Computational and Structural Biotechnology Journal
Published
2025-01-01
DOI
https://doi.org/10.1016/j.csbj.2025.05.005
Citations
1
Primary Topic
Gut microbiota and health
Type
article
Field-Weighted Citation Impact
0.81

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article

From variability to stability: Sensitivity of network properties in IBD human gut microbiome studies

Astrid Dempfle, Theresa Geese
1 citations
Computational and Structural Biotechnology Journal
Gut microbiota and health
0.81
article

From variability to stability: Sensitivity of network properties in IBD human gut microbiome studies

Astrid Dempfle, Theresa Geese
article en
1 citations

Abstract

Caution is needed with network-based approaches, as even small variations, stemming from sources of microbiome variability, can affect results and reproducibility. The relatively stable dysbiosis in IBD could pose challenges for microbiome-directed therapies.

Computational and Structural Biotechnology JournalVol. 27
Christian-Albrechts-Universität zu Kiel (DE), University Hospital Schleswig-Holstein (DE), University of Lübeck (DE)
Deutsche Forschungsgemeinschaft
Zero hunger
Openalex Percentile: Top 28%
Gut microbiota and health
0.81
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