Method development for the detection of anti-drug antibodies against a therapeutic peptide: assay format selection
This study highlighted advantages and limitations of each ADA assay format for peptide drugs and evaluated the performance of different assay formats in the assay development process to aid in the selection of the best fit-for-purpose assay formats for preclinical and clinical phases.
Authors
- Yan Mao
- Kelly Coble (ORCID: https://orcid.org/0000-0002-1796-7117)
- Fangfang Chen (ORCID: https://orcid.org/0000-0003-0830-9320)
- Xiaolong He (ORCID: https://orcid.org/0000-0002-4599-6599)
Institutions
- Boehringer Ingelheim (Taiwan) (TW)
Publication Details
- Journal
- Bioanalysis
- Published
- 2025-04-18
- DOI
- https://doi.org/10.1080/17576180.2025.2501937
- Primary Topic
- Biosimilars and Bioanalytical Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00