Pathogenetic characteristics and related risk factors of incisional infection after surgery for acute intestinal obstruction and construction of prediction model

Gram-negative bacteria constitute the primary causative agents of postoperative incisional infections in patients with acute intestinal obstruction. Moreover, these bacteria exhibit significant resistance to commonly used antibiotics. To mitigate the risk of such infections, clinicians should prioritize the monitoring of gram-negative bacterial growth. Prophylactic antibiotic administration can further reduce the incidence of these infections. Additionally, a predictive model incorporating six key variables-age ≥ 60 years, diabetes mellitus, operative time ≥ 3 h, colorectal obstruction, enterostomy, and HGB-can aid in identifying high-risk patients. This model enables clinicians to implement targeted early monitoring and preventive strategies, ultimately improving patient outcomes.