Features of the course of relapsing polychondritis (clinical case)

Relapsing polychondritis is a rare disease of autoimmune nature. At this stage, the problems of understanding the pathophysiology of relapsing polychondritis, its diagnosis, assessment of activity and prognosis, as well as treatment have not been resolved. The disease develops through exacerbation of remissions. It is characterized by clinical polymorphism, requiring a team approach from specialists from different specialties. Manifesta-tions usually occur gradually over time, and their frequency depends on the duration, activity and severity of the disease. Clinical heterogeneity of the disease is a source of diagnostic errors. The differential diagnosis in most cases concerns the involvement of each organ, which may appear immediately in a particular patient, but in most cases appears gradually, with an average of two symptoms at the onset of the disease. Purpose of the study: analysis of a clinical case of relapsing polychondritis, the clinical picture, the need for early diagnosis and the prescription of pathogenetic therapy. The article discusses our own clinical observation of relapsing polychondritis identified in a 62-year-old patient. A differential diagnosis was made between the patient’s disease, systemic scleroderma and necrotizing vasculitis.

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Publication Details

Journal
University proceedings Volga region Medical sciences
Published
2025-01-01
DOI
https://doi.org/10.21685/2072-3032-2025-1-7
Primary Topic
Otitis Media and Relapsing Polychondritis
Type
article
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article

Features of the course of relapsing polychondritis (clinical case)

Olga G. Radaykina, I.K. Fazlova, N. N. Guranova, A.A. Usanova et al.
University proceedings Volga region Medical sciences
Otitis Media and Relapsing Polychondritis
article

Features of the course of relapsing polychondritis (clinical case)

Olga G. Radaykina, I.K. Fazlova, N. N. Guranova, A.A. Usanova, Ekaterina V. Veshkina
article en

Abstract

Relapsing polychondritis is a rare disease of autoimmune nature. At this stage, the problems of understanding the pathophysiology of relapsing polychondritis, its diagnosis, assessment of activity and prognosis, as well as treatment have not been resolved. The disease develops through exacerbation of remissions. It is characterized by clinical polymorphism, requiring a team approach from specialists from different specialties. Manifesta-tions usually occur gradually over time, and their frequency depends on the duration, activity and severity of the disease. Clinical heterogeneity of the disease is a source of diagnostic errors. The differential diagnosis in most cases concerns the involvement of each organ, which may appear immediately in a particular patient, but in most cases appears gradually, with an average of two symptoms at the onset of the disease. Purpose of the study: analysis of a clinical case of relapsing polychondritis, the clinical picture, the need for early diagnosis and the prescription of pathogenetic therapy. The article discusses our own clinical observation of relapsing polychondritis identified in a 62-year-old patient. A differential diagnosis was made between the patient’s disease, systemic scleroderma and necrotizing vasculitis.

University proceedings Volga region Medical sciences(1)
Openalex Percentile: Top 84%
Otitis Media and Relapsing Polychondritis
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Features of the course of relapsing polychondritis (clinical case) — Olga G. Radaykina, I.K. Fazlova, et al. · University proceedings Volga region Medical sciences (2025) | TGRS Research Map | TGRS