Effect of Migraine Abortive Drugs on Benign Paroxysmal Positional Vertigo Odds: A Database Analysis

This study shows that, among patients with vestibular disorders, migraine patients with BPPV are more often exposed to triptans, and less to CGRP antagonists, than those without BPPV. Triptans may increase the prevalence of BPPV by potentiating vasoconstriction during migraine attacks, which may result in inner ear ischemia and alterations of endolymphatic pressure, while CGRP antagonists do not. Therefore, CGRP antagonists may be preferable over triptans for preventing BPPV in migraine patients.