ON THE IMPORTANCE OF CARDIOVASCULAR RISK FACTORS FOR THE ACUTE KIDNEY INJURY RESOLUTION DURING MYOCARDIAL INFARCTION IN MALES UNDER 60 YEARS OLD

Acute kidney injury negatively affects the prognosis of myocardial infarction. Purpose of the study. To study the structural features of the main and additional risk factors for cardiovascular diseases and their importance for resolving acute kidney injury in myocardial infarction in males under 60 years old in order to clarify the prognosis, improve prevention and outcomes. Material and Methods. The study included males aged 38-60 years old with type I myocardial infarction complicated by acute kidney injury. The patients were divided into two age-matched groups. The study group consisted of 21 patients with restored renal function during follow–up (56 days), the control group consisted of 109 patients without it. A comparative analysis of the structure of the main and additional risk factors for cardiovascular pathology in the selected groups was performed, as well as an analysis of their impact on the likelihood of renal function recovery during the follow-up period. Results. The compared groups differed in the frequency of smoking (71.4% in the study group and 89.9% in the control group; p=0.02), overweight (71.4% and 55.0%, respectively; p=0.03), and obesity (28.5% and 48.6%; p=0.046), under the age of 45 years old (38.1% and 14.7%; p=0.01), hereditary hypertension (81.0% and 56.0%; p=0.03); myocardial infarction in summer (47.6% and 13.8%; p=0.002) and winter (14.3% and 43.1%; p=0.002) periods of unstable angina (9.5% and 44.4%; p=0.003); balloon angioplasty and stenting (42.9% and 20.2%; p=0.03), as well as bypass surgery (0% and 22.0%; p=0.02) of coronary arteries, concomitant chronic obstructive lung diseases (9.5% and 34.9%, p=0.02); uro- (0% and 11.9%, p=0.01) and cholelithiasis (0% and 2.8%, p=0.01) in the anamnesis. Conclusions. The probability of restoring kidney function increased in non-smoking males under 45 years old with a hereditary history of hypertension, overweight without obesity, in the summer, with a less aggressive and short course of coronary heart disease and adequate treatment. These factors should be used for predictive modeling of kidney function in myocardial infarction.