CCP1 loss in bone marrow mesenchymal stem cells inhibited osteogenic differentiation by enhancing microtubule glutamylation
We propose that CCP1 plays a critical role in regulating BMSCs differentiation and promotes osteogenesis by modulating the post-translational modifications of tubulin, with a view to provide new targets for the prevention and treatment of hard tissue diseases.
Authors
- Xuekui Wang (ORCID: https://orcid.org/0000-0002-9149-7002)
- Hui‐Yuan Wu (ORCID: https://orcid.org/0000-0002-5586-8857)
- Cancan Pan
- Xuyan Gong
- Yao Sun (ORCID: https://orcid.org/0000-0002-9299-0229)
Institutions
- Tongji University (CN)
Publication Details
- Journal
- Cells Tissues Organs
- Published
- 2025-05-10
- DOI
- https://doi.org/10.1159/000546259
- Citations
- 1
- Primary Topic
- Ubiquitin and proteasome pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.81