Comparative analysis of tissue damage and inflammatory response for transoral laser microsurgery versus open surgery in the management of early-stage laryngeal cancer

This study demonstrated that in early-stage laryngeal cancer, TLM treatment results in a reduced inflammatory response, less tissue damage, and lower stress levels, as indicated by decreased levels of hs-CRP, IL-6, and cortisol, compared to OS treatment. These findings suggest that TLM has the potential to facilitate a quicker recovery and improve patient-reported outcomes compared to OS.

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Publication Details

Journal
Discover Oncology
Published
2025-05-10
DOI
https://doi.org/10.1007/s12672-025-02557-5
Primary Topic
Head and Neck Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparative analysis of tissue damage and inflammatory response for transoral laser microsurgery versus open surgery in the management of early-stage laryngeal cancer

Jiawei Gui, Jingchun Ge, Hui Xiao
Discover Oncology
Head and Neck Cancer Studies
article

Comparative analysis of tissue damage and inflammatory response for transoral laser microsurgery versus open surgery in the management of early-stage laryngeal cancer

Jiawei Gui, Jingchun Ge, Hui Xiao
article en

Abstract

This study demonstrated that in early-stage laryngeal cancer, TLM treatment results in a reduced inflammatory response, less tissue damage, and lower stress levels, as indicated by decreased levels of hs-CRP, IL-6, and cortisol, compared to OS treatment. These findings suggest that TLM has the potential to facilitate a quicker recovery and improve patient-reported outcomes compared to OS.

Discover OncologyVol. 16(1)
Harbin Medical University (CN), Second Affiliated Hospital of Harbin Medical University (CN), Heilongjiang University (CN)
Good health and well-being
Openalex Percentile: Top 87%
Head and Neck Cancer Studies
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