Comparative analysis of tissue damage and inflammatory response for transoral laser microsurgery versus open surgery in the management of early-stage laryngeal cancer
This study demonstrated that in early-stage laryngeal cancer, TLM treatment results in a reduced inflammatory response, less tissue damage, and lower stress levels, as indicated by decreased levels of hs-CRP, IL-6, and cortisol, compared to OS treatment. These findings suggest that TLM has the potential to facilitate a quicker recovery and improve patient-reported outcomes compared to OS.
Authors
- Jiawei Gui (ORCID: https://orcid.org/0000-0003-3016-0462)
- Jingchun Ge (ORCID: https://orcid.org/0000-0002-3492-2156)
- Hui Xiao (ORCID: https://orcid.org/0000-0002-1465-4596)
Institutions
- Harbin Medical University (CN)
- Second Affiliated Hospital of Harbin Medical University (CN)
- Heilongjiang University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-10
- DOI
- https://doi.org/10.1007/s12672-025-02557-5
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00