Epitope-based antibody development against metalloproteinases and phospholipases A2 from Deinagkistrodon acutus venom
The EpiMPLA epitope represents a promising candidate for generating neutralizing antibodies against <i>D. acutus</i>venom, demonstrating its potential to address critical gaps in current antivenom therapy. These findings not only validate the feasibility of epitope-based antivenom development but also pave the way for further research to optimize this strategy.
Authors
- Xia Liu (ORCID: https://orcid.org/0000-0002-3110-9602)
- Haiting Zhu (ORCID: https://orcid.org/0000-0002-5840-2251)
- Xiaodong Yu (ORCID: https://orcid.org/0000-0002-9827-9454)
- Qiyi He (ORCID: https://orcid.org/0000-0003-3567-5772)
- Zhiyuan Tai
- Yuexin Pan
- Mengqing Wang (ORCID: https://orcid.org/0009-0003-1575-9052)
Institutions
- Chongqing Normal University (CN)
Publication Details
- Journal
- The Journal of venomous animals and toxins including tropical diseases
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1590/1678-9199-jvatitd-2024-0060
- Citations
- 1
- Primary Topic
- Venomous Animal Envenomation and Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Natural Science Foundation of Chongqing