Effects of albumin-bound paclitaxel combined with Sophora subprostrate polysaccharide on inflammatory factors and immune function in breast cancer rats
Albumin-bound paclitaxel combined with Sophora subprostrate polysaccharide can reduce the local inflammation level, promote the proportion of CDB + T cells and NK cells and cell killing function, reduce the proportion of MDSC and immunosuppressive level, enhance the anti-tumor immune function of tumor-bearing mice, and slow the growth of tumors.
Authors
- Ling-Zhijie Kong (ORCID: https://orcid.org/0000-0002-5397-7937)
- Kaichun Li (ORCID: https://orcid.org/0000-0001-6442-4388)
- Wenyan Yu (ORCID: https://orcid.org/0000-0003-2743-3693)
- Zhiyong Zhang (ORCID: https://orcid.org/0000-0001-8576-1607)
- Zhuolin Li (ORCID: https://orcid.org/0009-0009-6991-3653)
- Chaozheng Ding
- Ying Zheng (ORCID: https://orcid.org/0000-0002-5264-6431)
Institutions
- Huazhong University of Science and Technology (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-05-10
- DOI
- https://doi.org/10.1007/s12672-025-02539-7
- Citations
- 2
- Primary Topic
- Flavonoids in Medical Research
- Type
- article
- Field-Weighted Citation Impact
- 2.79