Application of machine learning for the analysis of peripheral blood biomarkers in oral mucosal diseases: a cross-sectional study

Our study identified significant associations between the contents of VB2, VB3, VB5, Serum Fe, Serum Zn, and other micronutrients and oral mucosal lesions. It suggested that regulating these micronutrient levels could be essential for preventing and curing such lesions. The Random Forest model demonstrated high accuracy (94.68%) in classifying disease groups, emphasizing the potential of machine learning to enhance diagnostic precision in oral mucosal diseases. Future research should focus on validating these findings in larger cohorts and exploring alternative machine-learning algorithms to improve diagnostic accuracy further.

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Publication Details

Journal
BMC Oral Health
Published
2025-05-10
DOI
https://doi.org/10.1186/s12903-025-06095-y
Citations
1
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
2.48
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article

Application of machine learning for the analysis of peripheral blood biomarkers in oral mucosal diseases: a cross-sectional study

Haojie Pan, Xiaomin Xu, Fenjing Sun, Xi Ding et al.
1 citations
BMC Oral Health
AI in cancer detection
2.48
article

Application of machine learning for the analysis of peripheral blood biomarkers in oral mucosal diseases: a cross-sectional study

Haojie Pan, Xiaomin Xu, Fenjing Sun, Xi Ding, Liang‐Fu Huang, Zhuo Cao, Huiyu Yao, Wan Wu
article en
1 citations

Abstract

Our study identified significant associations between the contents of VB2, VB3, VB5, Serum Fe, Serum Zn, and other micronutrients and oral mucosal lesions. It suggested that regulating these micronutrient levels could be essential for preventing and curing such lesions. The Random Forest model demonstrated high accuracy (94.68%) in classifying disease groups, emphasizing the potential of machine learning to enhance diagnostic precision in oral mucosal diseases. Future research should focus on validating these findings in larger cohorts and exploring alternative machine-learning algorithms to improve diagnostic accuracy further.

BMC Oral HealthVol. 25(1)
Wenzhou Medical University (CN), First Affiliated Hospital of Wenzhou Medical University (CN)
Zero hunger
Openalex Percentile: Top 11%
AI in cancer detection
2.48
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