Resection of a singular metachronous testicular metastasis of prostate cancer: A case report
We present the case of a 66-year-old patient with a biochemical recurrence of prostate cancer manifesting as an asymptomatic testicular metastasis. Two years after radical prostatectomy and salvage radiation, the prostate-specific antigen (PSA) level rose to 1.07ng/ml. PSMA PET/CT scan showed tracer accumulation in the left testicle. Inguinal orchiectomy confirmed the metastasis. After being non-detectable, the PSA level increased five months after orchiectomy, with PSMA PET/CT revealing positive iliac lymph nodes. In summary, the presented case illustrates orchiectomy as a metastasectomy. However, apart from a transient decrease in PSA, no medium-term oncological advantage could be seen.
Authors
- Isabel Brinkmann
- Michael Chaloupka (ORCID: https://orcid.org/0000-0002-8814-6412)
- Stephan Ledderose (ORCID: https://orcid.org/0000-0001-7313-2088)
- Can Aydogdu (ORCID: https://orcid.org/0009-0003-1486-183X)
- Maria Apfelbeck (ORCID: https://orcid.org/0000-0002-9223-9291)
- Benedikt Ebner (ORCID: https://orcid.org/0000-0003-2126-7305)
- Christian Georg Stief (ORCID: https://orcid.org/0000-0003-3291-9460)
- Julian Marcon (ORCID: https://orcid.org/0000-0001-5304-817X)
- Marc Anwar Kidess (ORCID: https://orcid.org/0009-0005-2072-5521)
- Marie Semmler (ORCID: https://orcid.org/0009-0003-5634-3627)
- Nikolaos Pyrgidis
Institutions
- LMU Klinikum (DE)
- München Klinik (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- Current Problems in Cancer Case Reports
- Published
- 2025-05-10
- DOI
- https://doi.org/10.1016/j.cpccr.2025.100370
- Primary Topic
- Testicular diseases and treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00