Sensitivity and specificity of immunohistochemistry for the diagnosis of filamentous fungal infections
Anti-Aspergillus IHC was highly sensitive and specific in its ability to distinguish Aspergillus from other similar-appearing hyaline molds, including Fusarium and Scedosporium species. Anti-Rhizopus IHC was moderately sensitive and highly specific, while anti-Candida IHC was highly sensitive but had minimal specificity.
Authors
- Alvaro C. Laga (ORCID: https://orcid.org/0000-0003-1282-2274)
- Victoria L Thomas
- Isaac H. Solomon (ORCID: https://orcid.org/0000-0003-3432-0902)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
Publication Details
- Journal
- American Journal of Clinical Pathology
- Published
- 2025-05-10
- DOI
- https://doi.org/10.1093/ajcp/aqaf037
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health