Pentraxin-3 and C-reactive protein plasma levels predict survival in older adults with or without metabolic syndrome – results of the PolSenior2 substudy
Our study suggests that in the age-advanced Caucasian population, the inflammatory status with increased plasma levels of both PTX-3 and CRP is associated with a higher risk of all-cause mortality, regardless of the occurrence of MS. However, due to the retrospective study design, these results require confirmation in prospective studies with an analysis of the underlying causes of death.
Authors
- Aleksander Jerzy Owczarek (ORCID: https://orcid.org/0000-0003-1179-6932)
- Hanna Kujawska‐Danecka (ORCID: https://orcid.org/0000-0002-1416-620X)
- Małgorzata Mossakowska (ORCID: https://orcid.org/0000-0002-9340-3188)
- Andrzej Więcek (ORCID: https://orcid.org/0000-0002-8625-4188)
- Jerzy Chudek (ORCID: https://orcid.org/0000-0002-6367-7794)
- Magdalena Olszanecka‐Glinianowicz (ORCID: https://orcid.org/0000-0001-5632-5590)
- Anna Chudek (ORCID: https://orcid.org/0000-0002-6140-4602)
- Tomasz Roman Zdrojewski (ORCID: https://orcid.org/0000-0001-6015-8561)
- Monika Puzianowska‐Kuźnicka (ORCID: https://orcid.org/0000-0001-5295-3848)
- Anna Ochmann (ORCID: https://orcid.org/0000-0002-2891-3202)
Institutions
- Medical University of Silesia (PL)
- International Institute of Molecular and Cell Biology (PL)
- Postgraduate School of Molecular Medicine (PL)
- Mossakowski Medical Research Institute, Polish Academy of Sciences (PL)
- Gdańsk Medical University (PL)
- Polish Academy of Sciences (PL)
Publication Details
- Journal
- Immunity & Ageing
- Published
- 2025-05-08
- DOI
- https://doi.org/10.1186/s12979-025-00509-9
- Citations
- 1
- Primary Topic
- Biomarkers in Disease Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.80