Fecal Virome of Southeastern Maned Sloth (Bradypus crinitus) (Pilosa: Bradypodidae)
We report a viral metagenomic analysis of fecal samples from Bradypus crinitus (Pilosa: Bradypodidae), a recently described sloth species that occurs in the Atlantic Forest of Espírito Santo and Rio de Janeiro states, Southeast Brazil. Through Illumina sequencing, we generated a total of 2,065,344 raw reads, of which 945,386 reads (45.77%) passed the quality and size filter. The highest proportion of them was assigned to Eukarya, followed by Bacteria and only a small proportion to Virus. However, we identified 24 viral families using distinct taxonomic assignment tools, including phages and vertebrate viruses, such as retroviruses and papillomaviruses. Also, we identified four bacterial genus already associated with disease in sloths. Our study sheds light on the microbiome of a previously unexplored species, further contributing to the comprehension of metagenomic global diversity.
Authors
- Marcelo A. Soares (ORCID: https://orcid.org/0000-0002-9013-2570)
- Filipe Romero Rebello Moreira (ORCID: https://orcid.org/0000-0002-7162-5070)
- Carlos R. Ruiz-Miranda (ORCID: https://orcid.org/0000-0001-7360-0304)
- Gabriel Medeiros (ORCID: https://orcid.org/0000-0002-1216-3662)
- Thamiris dos Santos Miranda (ORCID: https://orcid.org/0000-0002-5896-5900)
- Matheus Augusto Calvano Cosentino (ORCID: https://orcid.org/0000-0001-9372-6561)
- Victor Wanderkoke
- Francine Bittencourt Schiffler (ORCID: https://orcid.org/0000-0002-6177-163X)
- Déa Luiza Girardi (ORCID: https://orcid.org/0000-0003-4808-3231)
- Mirela D’arc (ORCID: https://orcid.org/0000-0003-3644-0246)
- Ricardo Mouta (ORCID: https://orcid.org/0000-0001-6029-8193)
- André F. Santos (ORCID: https://orcid.org/0000-0003-3372-1552)
- Talitha Mayumi Francisco (ORCID: https://orcid.org/0000-0001-8609-7859)
- Amanda Coimbra (ORCID: https://orcid.org/0000-0002-2133-7492)
- Suelen Sanches Ferreira (ORCID: https://orcid.org/0009-0007-3440-8230)
- Flávio Landim Soffiati
Institutions
- Universidade Federal do Rio de Janeiro (BR)
- State University of Norte Fluminense (BR)
- Instituto Nacional de Câncer - INCA (BR)
Publication Details
- Journal
- Genetics and Molecular Biology
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1590/1678-4685-gmb-2024-0183
- Citations
- 1
- Primary Topic
- Bacteriophages and microbial interactions
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Petrobras
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Universidade Federal do Rio de Janeiro