The Hidden Threat in Immunoassays: A Case of Persistent False-Positive CK-MB.
This case underscores the critical importance of recognizing heterophilic antibody interference in immunoassays. The use of appropriate diagnostic approaches, such as blocking antibodies, cross-platform testing, and the integration of additional diagnostic markers, is essential to prevent misdiagnosis and ensure accurate clinical decision-making.
Authors
- Zhihui Zhong (ORCID: https://orcid.org/0000-0002-5627-2377)
- Jianwen Liu (ORCID: https://orcid.org/0000-0002-5899-8059)
- Wenfeng Huang (ORCID: https://orcid.org/0000-0002-3194-4368)
- Weiqiang Huang (ORCID: https://orcid.org/0000-0003-3877-5920)
- Siwei Xue
- Degui Ou
Institutions
- Zunyi Medical University (CN)
- Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine (CN)
- Huizhou Central People's Hospital (CN)
- Baoding People's Hospital (CN)
- Huizhou University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-01
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00