Grading T Lymphocyte-Mediated Acute Interstitial Nephritis Following Checkpoint Inhibitor Therapy.
This study indicates that nephrotoxicity due to CPI treatment is characterized by T lymphocyte-mediated AIN, with the majority being grade 1 AIN according to the modified Banff criteria. Most patients showed some renal functional recovery in response to steroid treatment.
Authors
- Ping L. Zhang (ORCID: https://orcid.org/0000-0002-6177-9244)
- Yazan Al-Othman
- B. D. Metcalf
- Olaf Kroneman
- Sami Zarouk
- Jeffery M Gold
- Hassan Kanaan
- Wei Li (ORCID: https://orcid.org/0000-0002-6960-7404)
Institutions
- Northwell Health (US)
- Royal Oak Community Coalition (US)
Publication Details
- Journal
- PubMed
- Published
- 2025-03-01
- Primary Topic
- Nephrotoxicity and Medicinal Plants
- Type
- article
- Field-Weighted Citation Impact
- 0.00