Investigating endogenous immune-mediated monocyte memory in rheumatoid arthritis
These data highlight how innate reprogramming during 'sterile' inflammatory diseases contributes to chronicity, uncovering pathways unique to endogenous immune triggers that could provide disease-specific points of intervention without engendering global immune suppression.
Authors
- Wyatt W. Yue (ORCID: https://orcid.org/0000-0001-6959-6007)
- Steve Sansom
- Linda W. Jennings (ORCID: https://orcid.org/0000-0002-4476-645X)
- Anja Schwenzer (ORCID: https://orcid.org/0000-0001-6375-924X)
- Carl S. Goodyear (ORCID: https://orcid.org/0000-0001-5926-5941)
- Calliope Athena Dendrou (ORCID: https://orcid.org/0000-0003-1179-4021)
- Sarah Davidson (ORCID: https://orcid.org/0000-0001-7453-9779)
- Adam P. Cribbs (ORCID: https://orcid.org/0000-0001-5288-3077)
- Karim Raza (ORCID: https://orcid.org/0000-0003-1570-1232)
- Anna M. Marzeda (ORCID: https://orcid.org/0000-0002-5270-9797)
- Amélie M. Julé (ORCID: https://orcid.org/0000-0003-2605-6726)
- Kieran Woolcock (ORCID: https://orcid.org/0000-0003-3912-3289)
- Kim S. Midwood (ORCID: https://orcid.org/0000-0002-8813-2977)
- Nan Yang (ORCID: https://orcid.org/0000-0003-4237-4513)
- Jean-Baptiste Richard (ORCID: https://orcid.org/0000-0002-4052-9772)
- Bogdan S Didov
Institutions
- Nuffield Orthopaedic Centre (GB)
- University of Oxford (GB)
- Arthritis UK (GB)
- NIHR Birmingham Biomedical Research Centre (GB)
Publication Details
- Journal
- Annals of the Rheumatic Diseases
- Published
- 2025-05-10
- DOI
- https://doi.org/10.1016/j.ard.2025.03.016
- Citations
- 7
- Primary Topic
- Immune responses and vaccinations
- Type
- article
- Field-Weighted Citation Impact
- 5.58
Funders
- Kennedy Trust for Rheumatology Research
- Versus Arthritis