Characterization of the intestinal microorganism in patients with congenital intestinal atresia: the preliminary exploration for establishment and influence of initial intestinal flora in newborns
The distinct microbial profiles observed among the three groups suggest that the establishment of neonatal intestinal flora may result from a combination of placental transmission and digestive tract colonization. Functional pathway analysis suggested these microbial metabolic differences may exert pleiotropic effects, demonstrating both protective roles in intestinal barrier function and potentially detrimental impacts on emotional modulation and glucose/lipid dysregulation.
Authors
- Xiao‐peng Ma (ORCID: https://orcid.org/0000-0002-9532-4870)
- Jiashu Liu (ORCID: https://orcid.org/0000-0003-4545-616X)
- Ling Zhou (ORCID: https://orcid.org/0000-0002-5851-9492)
- Ledao Zhu
- Feng Ren (ORCID: https://orcid.org/0000-0001-7523-0239)
- Yang Chen (ORCID: https://orcid.org/0000-0001-7661-5923)
- Xiangyu Zhang (ORCID: https://orcid.org/0000-0002-4858-5429)
- Zhiyong Wang (ORCID: https://orcid.org/0000-0001-9331-2211)
- Dong Xiao (ORCID: https://orcid.org/0000-0003-0344-7206)
- Qianghui Liao
- Jinlong Yao
Institutions
- Shenzhen Children's Hospital (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-05-10
- DOI
- https://doi.org/10.1186/s12866-025-04006-3
- Primary Topic
- Intestinal Malrotation and Obstruction Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00