Prognostic impact of lymph node and surgical margin in patients with perihilar cholangiocarcinoma

In patients with curatively resected for PHCC, R1 resection margin does not influence OS in patients with LN metastasis even when radical resection was achieved. Consequently, the risk of highly invasive procedures aimed at achieving R0 margins should be judiciously weighed against potential morbidity risk in patients with LN metastasis, as aggressive surgical strategies may not translate to survival benefits.

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Publication Details

Journal
European journal of medical research
Published
2025-05-09
DOI
https://doi.org/10.1186/s40001-025-02654-9
Citations
2
Primary Topic
Cholangiocarcinoma and Gallbladder Cancer Studies
Type
article
Field-Weighted Citation Impact
4.01

Funders

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article

Prognostic impact of lymph node and surgical margin in patients with perihilar cholangiocarcinoma

Yifei Yang, Liang Mao, Jianjie Sheng, Chenglin Lu et al.
2 citations
European journal of medical research
Cholangiocarcinoma and Gallbladder Cancer Studies
4.01
article

Prognostic impact of lymph node and surgical margin in patients with perihilar cholangiocarcinoma

Yifei Yang, Liang Mao, Jianjie Sheng, Chenglin Lu, Xu Fu, Yudong Qiu, Abudumijit Aibaidula
article en
2 citations

Abstract

In patients with curatively resected for PHCC, R1 resection margin does not influence OS in patients with LN metastasis even when radical resection was achieved. Consequently, the risk of highly invasive procedures aimed at achieving R0 margins should be judiciously weighed against potential morbidity risk in patients with LN metastasis, as aggressive surgical strategies may not translate to survival benefits.

European journal of medical researchVol. 30(1)
Nanjing University of Chinese Medicine (CN), Nanjing Drum Tower Hospital (CN)
Nanjing University, Nanjing Drum Tower Hospital
Good health and well-being
Openalex Percentile: Top 7%
Cholangiocarcinoma and Gallbladder Cancer Studies
4.01
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Prognostic impact of lymph node and surgical margin in patients with perihilar cholangiocarcinoma — Yifei Yang, Liang Mao, et al. · European journal of medical research (2025) | TGRS Research Map | TGRS