Cross-sectional association between hs-CRP/HDL-C ratio and physical frailty among middle-aged and older adults: findings from a population-based study
Our findings suggest that a higher hs-CRP/HDL-C ratio is associated with an increased risk of frailty among middle-aged and older adults. Albumin and globulin partially mediate this relationship. Additionally, the nomogram developed in our study shows strong predictive ability for identifying individuals at high risk of frailty in this population.
Authors
- Yang Wang
- Jing Jing Su (ORCID: https://orcid.org/0000-0002-8242-811X)
- Yina Wang
Institutions
- Central South University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Frontiers in Public Health
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fpubh.2025.1564206
- Citations
- 3
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 3.67
Funders
- Central South University