Unveiling the molecular landscape of δ-thalassemia and δ-globin variants in southern China: novel mutations, gene spectrum, and implications for thalassemia diagnosis
The study reveals that δ-globin gene mutations are prevalence in the South China and necessitates integration of δ-globin screening into existing thalassemia prevention protocols.
Authors
- Zhongchan Lao
- Qixun Fang
- Lihong Zheng
- Yongjun Xiao (ORCID: https://orcid.org/0000-0002-9524-570X)
- Youqiong Li (ORCID: https://orcid.org/0000-0002-8640-7375)
- Liang Liang (ORCID: https://orcid.org/0000-0002-5072-423X)
- Xi He (ORCID: https://orcid.org/0000-0002-2604-3434)
- Lihua Ye (ORCID: https://orcid.org/0000-0001-6790-9743)
- Jinping Bai
- Ting Qin
Institutions
- The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
- Second People’s Hospital of Yibin (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fgene.2025.1584310
- Citations
- 1
- Primary Topic
- Hemoglobinopathies and Related Disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.63