Immune inflammatory regulation in Anti-NMDAR encephalitis: insights from transcriptome analysis
Transcriptome analysis reveals significant activation of peripheral immune-inflammatory pathways in anti-NMDAR encephalitis. INSL3 and TPT1 may serve as potential auxiliary diagnostic biomarkers, while monocyte, CD8+ T cell, and Treg infiltration likely synergistically drive disease progression.
Authors
- Shan Qiao (ORCID: https://orcid.org/0000-0003-1834-1834)
- Shanchao Zhang (ORCID: https://orcid.org/0000-0002-5543-4530)
- Aihua Wang (ORCID: https://orcid.org/0009-0002-4061-2979)
- Tao Xin
- Haiyun Li (ORCID: https://orcid.org/0000-0001-6803-4117)
- Jia Wang (ORCID: https://orcid.org/0009-0002-9910-1639)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Shandong Provincial QianFoShan Hospital (CN)
- Qilu Hospital of Shandong University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fneur.2025.1568274
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Shandong Province
- Shandong First Medical University