Systemic inflammation markers (SII and SIRI) as predictors of cognitive performance: evidence from NHANES 2011–2014
This study suggests a positive association between SII, SIRI, and cognitive function, with a more pronounced relationship for SIRI. These findings highlight the potential of SIRI as a novel, accessible marker for predicting cognitive impairment risk.
Authors
- Huanhuan Zhu (ORCID: https://orcid.org/0000-0002-2995-4911)
- Fengyin Zhang (ORCID: https://orcid.org/0009-0005-8581-1834)
- Yujie Li (ORCID: https://orcid.org/0000-0002-2359-2673)
- Xiaoyue Wang (ORCID: https://orcid.org/0000-0001-8978-9236)
- Zhan Lin (ORCID: https://orcid.org/0009-0002-4863-1306)
- Juan Li (ORCID: https://orcid.org/0000-0002-5775-9355)
- Qinghua Wen (ORCID: https://orcid.org/0009-0005-5800-6215)
- Simin Li
Institutions
- Guizhou University (CN)
- Zunyi Medical University (CN)
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fneur.2025.1527302
- Citations
- 6
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 6.27
Funders
- National Natural Science Foundation of China
- Centers for Disease Control and Prevention