Exploring fluoroquinolone resistance mechanisms and the effects of carbonyl cyanide 3-chlorophenylhydrazone (CCCP) in Acinetobacter baumannii
The findings underscore the urgent need for improved surveillance and treatment strategies due to the high prevalence of fluoroquinolone resistance. While CCCP demonstrated potential in restoring antibiotic susceptibility, further studies are needed to assess its clinical applicability and potential toxicity. Additionally, the study is limited by its focus on a single geographic region, and further investigations across broader populations are necessary to generalize these findings.
Authors
- Mohammad Sina Alikhani (ORCID: https://orcid.org/0000-0001-8017-3443)
- Jaber Hemmati (ORCID: https://orcid.org/0000-0003-3539-2238)
- Mohsen Nazari (ORCID: https://orcid.org/0000-0001-8990-7036)
- Amjad Ahmadi (ORCID: https://orcid.org/0000-0001-9722-8826)
- Mohammad Yousef Alikhani
- Seyyed Hamid Hashemi
Institutions
- Hamedan University of Medical Sciences (IR)
- Urmia University (IR)
- Urmia University of Medical Sciences (IR)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-05-09
- DOI
- https://doi.org/10.3389/fmed.2025.1527662
- Citations
- 3
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.77
Funders
- Hamadan University of Medical Sciences