Diagnostic and prognostic biomarkers in autoimmune hepatitis-associated cirrhosis: insights into TBil, CD38, IL-22, TSP-1, GAL-3, and Cyc-C

This study underscores the critical roles of TBil, CD38, and IL-22 in cirrhosis development among AIH patients and validates the diagnostic and prognostic significance of TSP-1, Gal-3, Cys-C, AIb, and PA in compensated cirrhosis. These biomarkers facilitate early risk identification and inform clinical decision-making, contributing to improved management and outcomes for AIH patients.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-05-09
DOI
https://doi.org/10.3389/fmed.2025.1564107
Citations
1
Primary Topic
Liver Diseases and Immunity
Type
article
Field-Weighted Citation Impact
1.32
Controls
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article

Diagnostic and prognostic biomarkers in autoimmune hepatitis-associated cirrhosis: insights into TBil, CD38, IL-22, TSP-1, GAL-3, and Cyc-C

Jiani Shi, Jingbo Fu, Chao He, Jun Shen
1 citations
Frontiers in Medicine
Liver Diseases and Immunity
1.32
article

Diagnostic and prognostic biomarkers in autoimmune hepatitis-associated cirrhosis: insights into TBil, CD38, IL-22, TSP-1, GAL-3, and Cyc-C

Jiani Shi, Jingbo Fu, Chao He, Jun Shen
article en
1 citations

Abstract

This study underscores the critical roles of TBil, CD38, and IL-22 in cirrhosis development among AIH patients and validates the diagnostic and prognostic significance of TSP-1, Gal-3, Cys-C, AIb, and PA in compensated cirrhosis. These biomarkers facilitate early risk identification and inform clinical decision-making, contributing to improved management and outcomes for AIH patients.

Frontiers in MedicineVol. 12
Jiaxing University (CN), First People's Hospital of Yuhang District (CN), Zhoushan Hospital (CN), First Hospital of Jiaxing (CN)
Zero hunger
Openalex Percentile: Top 21%
Liver Diseases and Immunity
1.32
DOIOpen Access PDFOpenAlex
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Diagnostic and prognostic biomarkers in autoimmune hepatitis-associated cirrhosis: insights into TBil, CD38, IL-22, TSP-1, GAL-3, and Cyc-C — Jiani Shi, Jingbo Fu, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS